Anterior Segment, Corneal and External Disorders
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Extraskeletal Osteoma of the Eyelid—A Rare Case Report

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Published Online: Oct 26th 2015 US Ophthalmic Review, 2015;8(2):139–41 DOI:
Authors: Sudhir Singh
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Article Information

Osteoma is a benign osteogenic lesion with a very slow growth, characterized by proliferation of either cancellous or compact bone. Depending on its location, osteoma may be classified as central, peripheral, or extraskeletal type. Osteoma has been reported in relation to the paranasal sinuses and less frequently with the orbit. We report a case of a 25-year-old female who developed extraskeletal osteoma on her left upper eyelid, without involvement of the paranasal sinuses or orbit. Extraskeletal osteoma of the eyelid is an extremely rare variety. The mass was surgically removed and sent for histopathologic examination, which showed osteoma. To the best of our knowledge, this is the first case of extraskeletal osteoma of the eyelid reported in the English language literature.


Extraskeletal osteoma, lid osteoma, Sudhir Singh


Case Report
A healthy 25-year-old female patient, with a 6-month history, reported with a chief complaint of left upper lid mass and droopiness. History revealed that the swelling initially started as a peanut size and had gradually increased to the present size. Ocular examination was suggestive of nontender, bony hard, noncompressible, nonfluctuant, and nonpulsatile swelling on the left upper lid (see Figure 1A and B). The superior, inferior, medial, and lateral margins were well palpable. Mass was nonadherent to orbit, and it could be digitally displaced horizontally or vertically (see Figures 1C and D). The size of the swelling was 25 × 15 × 10 mm.

There was a history of blunt trauma to the left upper lid, and 3 months before she noticed this swelling. There was no history of vision changes, ocular pain, pain with eye movement, or headaches. Her vision was 20/20 in both the eyes. Both the eyes underwent slit lamp examination and fundus was also normal.

Past ocular history and medical history were noncontributory.

Review of systems was negative.

The patient was operated under local anesthesia. Two silk sutures were taken near the lid margin to provide traction during surgery. The globe was secured with an entropion plate. Lid crease incision was performed superficial to tumor (see Figures 2A and B). The lesion was isolated from the surrounding tissue by blunt dissection. Dissection was easily carried out around the mass except for the lower portion, which was found adherent with tarsal plate (see Figures 2B–D). The tumor and its extent were identified. The lesion was excised completely (see Figure 2E). No communication with the orbit or sinuses could be identified.

The tarsal plate was sutured with 6-0 vicryl interrupted sutures. Skin was sutured with interrupted 6-0 vicryl sutures (see Figure 2F). Patient’s ptosis was mostly recovered on 14th postoperative day (see Figure 3B). Specimens sent for histopathologic examination and histopathologic findings were consistent with an osteoid osteoma.

Gross Examination
The tumor was an encapsulated nodular lesion 25 × 15 × 10 mm in size. The consistency was bony hard. The anterior surface was glistening— white to pink color and was smooth with rounded protuberance. The cross-sections of specimen could not be cut by scalpel (see Figure 4).

Microscopic Examination
Histologic examination shows compact and mature bone and marrow space filled by connective tissue (see Figure 5).

Osteoma is a benign slow-growing osteogenic lesion, composed of well-differentiated mature bone tissue, characterized by the proliferation

Trauma and Surgery

of compact or cancellous bone, almost exclusively found in the head and neck region. Central, peripheral, and extraskeletal are the three variants of osteoma. Trauma, inflammation, developmental disorders, and genetic defects are considered as the etiologic factors.1

Osteoma can occur at any age, but more frequently seen between the third and fifth decades. It has got a slight male predilection.2 Paranasal sinuses are the favorite locations of peripheral osteoma of the craniofacial region—frontal and ethmoidal sinuses being the common ones. External auditory canal, orbit, temporal bone, and pterygoid processes are the other locations.3 Primary orbital bone tumors constitute a very small percentage of all orbital tumors. More often, osteomas originate from the paranasal sinuses. Among the bony orbital tumors, fibrous dysplasias and osteomas are the most commonly encountered entities.4

The case we reported here was an extraskeletal osteoma of the eyelid, as it was located in the left upper lid without any communication to orbit or

paranasal sinuses. There was a history of blunt trauma to the left upper lid 3 months before this lid mass was noticed by the patient. The extraskeletal soft tissue osteoma usually develops within the muscle. In our case, extraskeletal osteoma probably was developed from orbicularis oculi of the left upper lid. During surgery, we found that this lesion was lying just beneath pretarsal muscle and anterior to tarsal palate. It was confined only to the eyelid. Extraskeletal osteoma of the lid is very rare. To the best of our knowledge, this is the first case of extraskeletal osteoma of the lid reported in the English language literature.

The osteoma is often slow growing and asymptomatic, diagnosed incidentally on radiographs. But later on, it can achieve a faster growth rate, as the rate of osteogenesis increases, and can cause deformation of the bone and compression of the adjacent structures. They usually appear

as unilateral, sessile or pedunculated, well-circumscribed, mushroomlike masses, ranging from 1.5 to 40 mm in diameter.5 All these features are consistent with the present case. During physical examination, tumor was confined to eyelid and boundaries were well defined and palpable. So we did not order for computed tomography scan and planned this case for an excisional biopsy.

The differential diagnoses in this case include osteoid osteoma, dermoid cyst, and lipoma. Osteoma of the orbit can be seen as a bony hard swelling.6 Dermoid cyst and lipoma are also seen as subcutaneous nodules in the lid, but they will be soft and fluctuant.7

Management of osteoma of the eyelid is complete excision with clear margin to establish the histopathologic diagnosis and prevent recurrence.

Article Information:

Sudhir Singh, MS, has no conflicts of interest to declare. No funding was received for the publication of this article.


Sudhir Singh, MS, Senior Consultant & HOD, Department of Ophthalmology, JW Global Hospital & Research Centre, Mount Abu, Rajasthan, India 307501.


This article is published under the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, adaptation, and
reproduction provided the original author(s) and source are given appropriate credit.
Compliance with Ethical Guidance: Informed consent was received from the patient involved in this study.




1. Shanavas M, Chatra L, Shenai P, et al., Multiple peripheral osteomas of forehead: report of a rare case, Ann Med Health Sci Res, 2013;3:105–7.
2. Wanyura H, Kaminski A, Stopa Z, Treatment of osteomas located between the anterior cranial base and the face, J Craniomaxillofac Surg, 2005;33:267–75.
3. Johann AC, de Freitas JB, de Aguiar MC, et al., Peripheral osteoma of the mandible: case report and review of the literature, J Craniomaxillofac Surg, 2005;33:276–81.
4. Selva D, White VA, O’Connell JX, Rootman J, Primary bone tumors of the orbit, Surv Ophthalmol, 2004;49(3):328–42.
5. Kerckhaert A, Wolvius E, van der Wal K, Oosterhuisa JW, Giant osteoma of the mandible: case report, J Craniomaxillofac Surg, 2005;33:282–5.
6. von Chamier G, Holl-Wieden A, Stenzel M, et al., Pitfalls in diagnostics of hip pain: osteoid osteoma and osteoblastoma, Rheumatol Int, 2010;30:395–400.
7. Sewell LD, Adams DC, Marks VJ, Subcutaneous forehead nodules: attention to the button osteoma and frontalis-associated lipoma, Dermatol Surg, 2008;34:791–8.
8. Sires BS, Benda PM, Stanley RB Jr, et al., Orbital osteoid osteoma, Arch Ophthalmol, 1999;117:414–5.

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