Welcome to the Spring edition of US Ophthalmic Review, introduced by Editorial Board member Cynthia Matossian, who spoke with us about the recent advances in the treatment of dry eye disease.
This edition features several articles around the latest updates in glaucoma, including an overview of the recent landmark trials and the role of 10-2 visual field testing. Priyanka Sood reviews the intraoperative complications that can occur with LASIK and Noel Alpins shares a case of predictable avoidable laser-assisted in situ keratomileusis surprise (PALS) syndrome. Steve Charles shares his techniques to improve outcomes and reduce complications in retinal detachment surgery and Lisa Nijm reviews the pathophysiological pathways underlying the inflammatory response in this condition.
Thank you to all of our contributing authors and reviewers. We’re now accepting submissions to our Fall edition; please visit our submission site for more information.
Foreword – Us Ophthalmic Review, Spring 2019
Welcome to the latest edition of US Ophthalmic Review, whose wide-ranging articles reflect the rapid pace of ophthalmologic research, as well as the scope of this field. Ophthalmology is unique in that practitioners are involved all aspects of patient care, from diagnosis to post-operative assessment and ongoing evaluation. We begin with one of our popular […]
Advances in Dry Eye Disease
Dry eye disease (DED) is one of the most common conditions encountered by ophthalmologists, with up to 50% of patients reporting symptoms.1 For many decades, DED was thought to be a simple condition caused by reduction of the aqueous phase of the tear film, but it has been redefined as: “a multifactorial disease of the tears […]
Understanding the Science Behind the Inflammatory Cascade of Dry Eye Disease
Dry eye disease (DED) is the one of the leading causes of adult visits to ophthalmologists in the USA, with an estimated prevalence of 5–50% in adults over the age of 50 years.1 Studies have estimated over 16 million patients have been diagnosed with DED, even in patients as young as 18–34.1 As the “Baby Boom” population […]
Failure Modes in Retinal Detachment Surgery
Poor visualization is a common cause of failed retinal detachment surgery, both because of failure to identify and treat retinal breaks and because of residual vitreoretinal traction (see Figure 1). Cataract, especially cortical and posterior subcapsular cataract, limits crucial visualization of the peripheral retina.1,2 Combined phacoemulsification and vitrectomy are commonly performed outside the USA, but often yield […]
Flap Complications from Femtosecond Laser-assisted in Situ Keratomileusis
Lamellar procedures have their origins in the 1960s, when they were introduced by Barraquer in Columbia.1 In the 1990s, Pallikaris and Buratto introduced the concept of combining a lamellar procedure with surface ablation excimer lasers,2,3 giving rise to laser-assisted in situkeratomileusis (LASIK) surgery. Several iterations and techniques have been developed since then, and over the […]
A Review of Recent Landmark Trials in Glaucoma
In recent years, the field of clinical glaucoma research has been geared towards investigating surgical intervention. Recent trials have focused on examining the outcomes of conventional glaucoma surgery, including trabeculectomy and glaucoma drainage devices. They have additionally explored the novel uses of minimally invasive glaucoma devices. This review presents an update on recent landmark glaucoma […]
A Rethink of 10-2 Visual Fields in Early Glaucoma
Visual field (VF) analysis of the central retina is being touted by some clinicians as an indispensible investigation in all glaucoma patients, irrespective of the stage of the disease.1 The functional tests to investigate glaucoma patients analyze the VFs to look for loss of sensitivity. In early cases of glaucoma and glaucoma suspects the programs […]
Beware of the “Wolf in Sheep’s Clothing” in Your Eye Clinic
Diplopia from comitant ocular deviations is a relatively common clinical presentation. On examination, the presence of a ductional deficit is suggestive of neuromuscular or neurogenic etiology. Without this deficit, the cause is usually attributed to the breakdown of previously well-controlled phoria. In some cases, however, the binocular diplopia is due to a more complex and […]
PALS Syndrome Post-LASIK
A 34-year-old male presented to the clinic for a second opinion regarding ongoing symptoms of glare, ghosting, starbursts, haloes and reduced contrast sensitivity three years post-laser-assisted in situ keratomileusis (LASIK) surgery. These symptoms were exacerbated under low light conditions, particularly driving at night, and he found a reduction in their effect when shining his cell […]
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