Trending Topic

23 mins

Trending Topic

Developed by Touch
Mark CompleteCompleted
BookmarkBookmarked
Luke G Qin, Michael T Pierce, Rachel C Robbins

The uvea is a vascular stratum that includes the iris, ciliary body and choroid. Uveitis is defined as inflammation of a part of the uvea or its entirety, but it is also used to describe inflammatory processes of any part of the eye, such as the vitreous or peripheral retina. The clinical taxonomy of uveitis […]

Bart Leroy, EURETINA 2022: RNA Interference Therapy for CEP290-IRD

Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied
Published Online: Sep 21st 2022

Prof. Bart Leroy (Ghent University, Ghent, Belgium) joined touchOPHTHALMOLOGY in an interview to speak about RNA interference therapy and its advantages in treating inherited retinal diseases caused by CEP290 mutations.

‘RNA Interference Therapy for CEP290-IRD’ was presented at EURETINA 2022, 1–4 September 2022 

  1. Could you tell us a little about inherited retinal diseases (IRD) caused by CEP290 mutations and the unmet needs in their treatment? (00:22)
  2. Could you explain the mechanism of action of RNA interference therapy? (02:20)
  3. What are the advantages and limitations of this strategy compared with other gene therapies in IRD? (05:48)
  4. What clinical evidence supports the use of RNA interference therapy? (08:02)
  5. What questions remain unanswered and what future studies are planned? (12:27)

Disclosures: Bart Leroy is a consultant for and receives grant/research support from ProQR Therapeutics.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Lisa Glass.

Filmed as a highlight of EURETINA 2022.

Share
Facebook
X (formerly Twitter)
LinkedIn
Via Email
Mark CompleteCompleted
BookmarkBookmarked
Copy LinkLink Copied

This Functionality is for
Members Only

Explore the latest in medical education and stay current in your field. Create a free account to track your learning.

Close Popup