Dry Eye Disease – Current Insights and Future Perspectives
Understanding the severity of keratitis and its impact in severe dry eye disease The target mechanisms that drive the pathophysiology of dry eye disease (DED) are principally tear film instability, tear hyperosmolarity, apoptosis and inflammation. These factors, respectively, lead to cell damage, nerve stimulation, cytokine release, matrix metalo-proteinase activation and goblet cell loss and form […]
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