Uveitis and Ocular Immunology
An Introduction to Uveitis and Ocular Immunology
Uveitis is a leading cause of irreversible blindness in the developed world. First-line treatment involves corticosteroids followed by immunosuppressant therapy and an anti-tumour necrosis factor-alpha (TNF-α agent). Further investigation into new immunotherapies targeting different immune components is promising for the future.
Browse the content below, to see leading experts discuss the latest data in video interviews and short articles from our conference hub. You can also view the selection of peer-reviewed articles from our journals. If you’re looking to learn more about the impact of these developments on patient outcomes, our educational activities are a great resource.
Uveitis and Ocular Immunology Content
Alay Banker, AAO 2018 – Developments in the treatment of uveitis
In the touchOPHTHALMOLOGY Fall issue of US Ophthalmic Review, Dr Alay Banker published an interesting review on “Emerging Treatments for Non-infectious Uveitis”. In this interview at AAO 2018, he discusses the side effects associated with steroidal treatments and how this impacts patient adherence. It is hoped that emerging non-steroidal drugs can alleviate some of these […]
Laser Flare Photometry – Clinical Use and Future Possibilities as a Biomarker
European Ophthalmic Review. 2018;12(Suppl 2):3–9
The importance of objective and quantitative measurement methods in uveitis – laser flare photometry Carl P Herbort Jr Centre for Ophthalmic Specialised Care at Clinic Montchoisi Teaching Centre, Lausanne, Switzerland; University of Lausanne, Lausanne, Switzerland Laser flare photometry (LFP) involves measuring the level of scattered light (in photons per millisecond [ph/ms]) from a laser beam […]
Emerging Treatments for Non-infectious Uveitis
US Ophthalmic Review. 2018;11(2):81–6 DOI: https://doi.org/10.17925/USOR.2018.11.2.81
Uveitis comprises a range of intraocular inflammatory conditions of both infectious and non-infectious origin that can result in irreversible ocular damage and impaired vision or blindness.1 Effective management is therefore vitally important to prevent ocular damage and preserve visual acuity and quality of life.1–3 Therapeutic management of uveitis is dictated by etiology and anatomic location.1 […]
Ocular Rosacea—a Review
US Ophthalmic Review, 2017;10(2):113–8 DOI: https://doi.org/10.17925/USOR.2017.10.02.113
Ocular rosacea is a chronic inflammatory disorder which may present in various manifestations such as chronic blepharoconjunctivitis, meibomian gland dysfunction, corneal vascularization, infiltration, scarring and, albeit rarely, even perforation. In nearly half to two thirds of cases it has been reported to occur in association with acne rosacea, a disease characterized by transient or persistent […]
Biologic Therapy in Uveitis
European Ophthalmic Review, 2016;10(1):17–8 DOI: http://doi.org/10.17925/EOR.2016.10.01.17
This last decade has seen truly significant changes in the understanding and management of uveitis, from the standardisation of diagnostic criteria that the Standardization of Uveitis Nomenclature (SUN) project has brought to the advent of novel therapeutic options that have revolutionised disease management.1,2 In this, the uveitis world is following the lead set by rheumatology […]
Symptoms and Signs of Anterior Uveitis
US Ophthalmic Review, 2013;6(1):33-37 DOI: http://doi.org/10.17925/USOR.2013.06.01.33
Anterior uveitis denotes intraocular inflammation that involves the iris (iritis), anterior part of the ciliary body (anterior cyclitis), or both (iridocyclitis). Primary site of inflammation, as determined clinically, is the anterior chamber and/or anterior vitreous.1 The standardization of uveitis nomenclature (SUN) working group has categorized uveitis according to the onset, duration, and course of the […]
Nepafenac in the Prevention and Treatment of Ocular Inflammation and Pain Following Cataract Surgery and in the Prevention of Post-operative Macular Oedema in Diabetic Patients
European Ophthalmic Review, 2012;6(3):169–72 DOI: http://doi.org/10.17925/EOR.2012.06.03.169
During ophthalmic surgery, surgical trauma causes activation of cyclo-oxygenase (COX) COX-1 and COX-2, which metabolise arachidonic acid to prostaglandins (PGs). PGs are mediators of the inflammatory response, and increased production of these molecules can result in discomfort, pain and ocular inflammation. As inhibitors of PGs, non-steroidal anti-inflammatory drugs (NSAIDs) are often employed by ophthalmic surgeons […]
Viral Aetiology in Anterior Uveitis – The Tip of an Iceberg?
European Ophthalmic Review, 2012;6(2):119–24 DOI: http://doi.org/10.17925/EOR.2012.06.02.119
Intraocular viral infections have various presentations. They may be detected as anterior uveitis, intermediate uveitis, acute retinal necrosis (ARN), progressive outer retinal necrosis (PORN) and neuroretinitis (see Figure 1).1,2 Anterior uveitis (AU) in most patients is either idiopathic or associated with HLA-B27 positivity. However, a viral cause of AU is often underestimated. The most common […]
Loteprednol Etabonate in Ocular Inflammation
US Ophthalmic Review, 2011,4(1):57-62 DOI: http://doi.org/10.17925/USOR.2011.04.01.57
Ocular inflammatory diseases significantly burden patients, family members, healthcare plans, ophthalmic clinics, and workplace productivity due to health-related absenteeism. The cost of prescription medicines for ocular allergy was estimated at over $200 million in the US in 2002, with a projected rise of 25% per year as prescription medicines continue to improve and show benefit […]
Journal articles and more to your inbox
Get the latest clinical insights from touchOPHTHALMOLOGYSign me up!