Corneal oedema is a common sign of acute or chronic corneal disease resulting from various aetiologies such as corneal endothelial dystrophy, prior surgery such as cataract surgery, metabolic disorders, toxicity or hypoxia. Measurement of central corneal thickness (CCT) is an objective and surrogate assessment for the evaluation of corneal oedema. The commonly used tools for the CCT measurements include ultrasonic pachymetry, anterior segment optical coherence tomography, specular microscopy and corneal tomography. Terahertz and mid-infrared technology have emerged recently for their applications on corneas. Instead of measuring CCT, they detect the changes of corneal water concentrations because their light wave spectrum is sensitive to water. The utility of these imaging systems as an adjuvant tool for the evaluation of corneal oedema, will be discussed in this article.
Corneal edema, corneal disease, corneal endothelial dystrophy, central corneal thickness, CCT, Terahertz, mid-infrared technology
Yu-Chi Liu, Lin Ke and Jodhbir S Mehta have nothing to disclose in relation to this article.
Double-blind peer review.
All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship of this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval to the version to be published.
Yu-Chi Liu, 20 College Road, Discovery Tower, Level 12, Singapore 169856. E: [email protected]
No funding was received in
the publication of this article.
25 October 2019
Related Content In Corneal Disorders
Paediatric Vernal Keratoconjunctivitis – The VEKTIS Study
European Ophthalmic Review. 2020;14(1):Online ahead of journal publication
Dominique Bremond-Gignac, MD, PhD, FEBO, is Professor of Ophthalmology and Head of the Department of Ophthalmology with a paediatric and ocular surface subspecialty at the University Hospital Necker–Enfants Malades and University of Paris in Paris, France. She graduated in pharmacology and statistics (MSc) and completed her PhD thesis in anatomy. Her activity is distributed across […]
Response to “Optical Lens Tinting—A Review of its Functional Mechanism, Efficacy, and Applications”
US Ophthalmic Review. 2020;13(1):16–7 DOI: https://doi.org/10.17925/USOR.2020.13.1.16
I was interested to read the review, “Optical Lens Tinting—A Review of its Functional Mechanism, Efficacy, and Applications” by Jared Raabe, Ashwini Kini, and Andrew Lee, which appeared in US Ophthalmic Review.1 I am the inventor of the FL–41 lens that features in the article. As the authors point out, the original design of the lens […]
Toxic Keratopathy with Bi-layer Corneal Calcific Infiltrates Caused by Proparacaine Abuse—A Case Report
US Ophthalmic Review. 2020;13(1):40–1 DOI: https://doi.org/10.17925/USOR.2020.13.1.40
Proparacaine is a topical anesthetic widely used in ophthalmic practice. Proparacaine is well tolerated with limited duration of use, but has potential to become a drug of abuse.1 Extended use has numerous corneal sequelae including stromal infiltrates, corneal melt, and endothelial cell loss.1–3 In this report we present a case of proparacaine-associated keratopathy that necessitated bilateral penetrating […]
Journal articles and more to your inbox
Get the latest clinical insights from touchOPHTHALMOLOGYSign me up!