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We are delighted to share the latest issue of touchREVIEWS in Ophthalmology, showcasing a diverse range of articles that highlight the innovation, interdisciplinary collaboration and continued advances driving progress in eye care today. We begin this issue with an important ...
Breast carcinoma is the most common cancer in females. An estimated 2.3 million new cases of breast carcinoma are diagnosed annually worldwide.1Â These patients have potential risks of ocular complications not only from the secondaries in the eye but also due ...
On 28 May 2024, enrolment in phase III clinical trials for sozinibercept in neovascular age-related macular degeneration (nAMD) was completed.1 These trials include two large multicentre, double-masked, randomized controlled trials (RCTs): COAST (OPT-302 with aflibercept in neovascular age-related macular degeneration; ClinicalTrials.gov ...
The uvea is a vascular stratum that includes the iris, ciliary body and choroid. Uveitis is defined as inflammation of a part of the uvea or its entirety, but it is also used to describe inflammatory processes of any part ...
The EURETINA 2024 Congress, held in Barcelona from September 19-22, brought together leading experts in ophthalmology to share the latest research and innovative treatments for retinal diseases. Among the highlights were several late-breaking abstracts that showcased promising advances in therapeutics for conditions such as retinopathy of prematurity (ROP), diabetic retinopathy (DR) and age-related macular degeneration (AMD). These studies not only demonstrated the efficacy and safety of novel treatment options but also addressed critical unmet needs in reducing patient burden and improving long-term outcomes.
Findings from a recent cohort study published in JAMA Network Open suggest that paediatric patients with uveitis are at significant risk of cataract development.
Recent advancements in publicly available artificial intelligence (AI) large language models (LLMs) have piqued the interest of the medical community. LLMs are 'trained' using massive datasets and can generate natural language text in response to free-text inputs. Conversational agents (chatbots), ...
Retinal pharmacotherapy encompasses various drug delivery routes that offer potential avenues for effective treatment (Figure 1). Among these, intravitreal injections have emerged as the predominant method employed in clinical practice.1Â They have established themselves as the primary approach for administering anti-vascular ...
Choroidal granuloma is a relatively rare manifestation of sarcoidosis. Cases of sarcoid granuloma may lack accompanying ocular inflammation and can mimic posterior segment tumours, leading to a delay in diagnosis and treatment. These lesions are typically steroid responsive,1Â and quick ...
Leber hereditary optic neuropathy (LHON) is a mitochondrially inherited optic nerve disease characterized by bilateral (sequential or simultaneous), subacute, painless central vision loss.1 LHON was first described in 1871 by the German ophthalmologist Theodor Leber.2 However, it was not until 1988 that ...
Reproxalap is a reactive aldehyde species (RASP) inhibitor believed to mitigate inflammatory conditions such as dry eye disease (DED), allergic conjunctivitis and uveitis.1 RASP are pro-inflammatory molecules that covalently bind to thiol and amino groups expressed on various receptors and ...
Corticosteroids are the best choice for treating various ocular conditions affecting the anterior and posterior segments of the eye.1Â Currently, different routes are available for ocular administration of corticosteroids. Topical application to the eye is the route of choice when ...
Varicella zoster virus is a double-stranded DNA herpesvirus that resides dormant in the sensory nerve ganglia after primary infection of varicella/chicken pox. While primary infection can be mild, on reactivation, the virus typically causes a painful vesicular rash called ...
Cataract interventions are among the most common surgical procedures performed worldwide, in developed or developing countries.1 In 2015, approximately 3.6 million cataract interventions were performed in the United States.2 In the next few years, age-related diseases are likely to rise in many ...
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